This will probably be my final post in Reddit before I aim to finish the game, because I notice quite a bit of posts that while aren't story spoilers, kind of kill exploration for me by telling me what exists.
Me in Night City
I'm about 64 hours in, I don't think I'm close to completing the game at all yet, and I don't want to know.
How I'm playing
I am playing the game with my own set of rules that I try my best to follow.

1. No fast travel
2. No multi-tasking, I focus on quests so I can follow the story better.
3. No cheesing enemy and bad AI - I try to have a fair fight, knowing the AI can be cheesed
4. Balance style and substance - I don't try to have the best stats, I try to find the average of looking good and good stats.
5. I'm playing on hard mode
6. No loading to try different dialogue choices, and if I make a mistake I stick with it. I'll know better in my next playthrough.
7. Driving in first person camera only
8. And of course, no guides, tips/tricks videos, google searches etc.
9. If the mission encourages stealth, I'll try to do it... until I mess up and then it's guns blazing.
10. If an NPC calls me or tells me something is urgent, I will treat it as such.

I find that this method of playing, with self imposed rules helps immerse myself more into the game world and feel like I'm a physical person in it. So with that being the case, my experience might be rather different from your own, unless I'm a lot less unique than I think.
Expectations
I went into Cyberpunk 2077 with pretty damn high expectations, in the months leading up to the big release day, I was almost unable to enjoy other games because of how pumped I was for Cyberpunk. From everything I heard, I had a pretty good picture of what kind of game it was. But many people were telling my in DeusEx to not expect Cyberpunk 2077 to scratch my Deus Ex "itch". As a big fan of Deus Ex, I kept this in mind as I replayed both the 2012 and 2015 entries of Deus Ex, as well as the original again leading up to Cyberpunk 2077.I am a huge Deus Ex fanI think a large portion of the players who are Deus Ex fans are also very pleased with Cyberpunk 2077. Although the storyline is very different, a lot more grounded and focused on people than multilayered conspiracies, and a lot more focused on small stories rather than large plotlines,
Story (No spoiler)
I am starting to like how neatly each plotline feels complete in Cyberpunk 2077, and you get this sense of making a real difference in the game's world and story every hour, every day playing. Deus Ex (especially the newer ones) had a lot of loose ends in plot lines and left a lot of mystery intentionally. I won't say if it's good or bad, but I like both approaches to story telling.
Combat & Gameplay
I'm enjoying the combat a lot, I don't stick to what works, I try to make each combat encounter different by changing weapons up and imposing arbitrary challenges to myself this way. The gunplay is great, and because I don't have a lot of health, I find myself jumping and running to evade enemy fire a lot, combat feels like a mix of parkour and fighting a lot of the time.
I find that an enemy scaling option might be useful feature/option for CDPR to consider, but I'm not sure if it would be bad for character progression. A lot of enemies, even cyberpsychos are severely under-leveled compared to me now and that's a bit of a shame.
Immersive Sim / RPG aspects
A lot of people are saying Cyberpunk 2077 is not an immersive sim, and some are saying it's not an RPG. I can't disagree more.
By definition, Cyberpunk 2077 is quite close to being an immersive sim but on a large scale. There's choice after choice, with actual impact to the isolated storylines and characters in each storyline to a degree I've never experienced in any game before. In some ways, I think Watch Dogs does a better job of allowing for emergent gameplay. But I can't truly say because I haven't delved deep into hacking in Cyberpunk as of this playthrough. I find more detailed bits of story and world building in Night City than I expected, it feels very much like Deus Ex Mankind Divided, but on a much larger scale.
As for it being an RPG, I've never felt as overwhelmed when it comes to a character building before. It's definitely more so an RPG than Ubisoft's new Assassin Creed games which people keep criticizing as being an RPG and not an Assassins Creed game. It really depends on where you draw the line. But I think Cyberpunk 2077 is quite definitely an RPG. It's at least on par with Witcher 3 on how RPG it is, and I think even more so.
World & Exploration
I've never played an open world game with this many buildings you can enter. It's so uncanny that I've had someone say the game is bad because you can't enter EVERY building. Which is both insane and unnecessary to ask for from a video game (not a simulation). I don't think people realize how many buildings are actual locations you can enter. A lot of them I believe are gated behind quests and gigs. So unless you have unlocked the necessary quest, they show as "Locked", and if you finish the quest it's still accessible in some cases later, and in some cases not.
I think a lot of people notice a large number of those "Locked" places and assumed they are all just fake doors. In my experience so far, I've noticed my world slowly opening up more and more. There's places I previously saw and couldn't enter that I can now. I'm not sure if 100% of the doors are actually going to be enterable (I doubt it) but a lot of them seem to be and I love that. It feels like I'm slowly exploring the city and at a better, managed pace than if everything was open from the start.
I also realized I was sent on a Gig to kill someone, and in that same place, I killed someone else... and it completed a quest unknowingly to me. What I realized happened was that - I had killed someone which I was supposed to do a boxing match with, and so the game just marked it as completed. I think CDPR found a good balance of locked areas and open areas to balance the number of times these occurrences are possible. It would suck if you were killing people who potentially gave you quests down the line without you knowing.
I know a lot of people are unfairly comparing this game to Rockstar open world games. I understand to an extent the reason for the complaints, but at the same time... I know this is an RPG. The complication comes because of how close this comes to a Rockstar open world that those comparisons are now being made. Nobody says Fallout is not a true open world game because nobody expects GTA minigames in Fallout, or nobody expects GTA minigames in The Outer Worlds. In a way, it's a good thing people are making that comparison. It's a testament to how close CDPR got to that without even aiming for it.
That being said, I think that "Gwent" and the Dice game in the previous Witcher games were a nice side activity that made it worth the time to travel from Inn to Inn. I think a lot of the regular store vendors who have useless food in Cyberpunk 2077 could really use a reason to visit like that.
Bugs & Optimization
This has been talked about to death now. So I'll keep it short, I've had 3 crashes in 60+ hours on PC and a variety of visual glitches like T-Posing, people in people, people in walls, cars in cars etc. But I'm still loving the game, and I know the patches will fix it.
I'm fortunate to have an RTX 3080, so I'm playing it very well. Right now... Cyberpunk is a very expensive game and I hope it changes soon so that more people can play it at it's best.
Nitpicks

1. All NPCs in every district seem to speak in the same way. I think they should have atleast some situational awareness...Civilians are pretty dumb. I know crowd simulation is hard and giving each complex logic is infeasible, but maaan are they dumb.
2. Only 2 god damn Joytoys? how is there a Map Marker legend made for 2 NPCs unless it was cut content. I'm not a horny teen, but this is like kind of underwhelming, the feature is right there just copy + paste and use the same cutscene. WHYY!? On that note, so many people who aren't joytoys keep telling me they want to sleep with me.
3. Fix the Junk disassemble perk to only do it to low cost junk.

Features Wish List

1. BarbeTattoo Artists
2. More Cyberware Surgery Cutscenes
3. Customizable Vehicles - Paint jobs, illegal mods like Nitrous boosts
4. The armor stands in Witcher 3 Blood & Wine in V's apartment to save outfits for later.
5. Customizable Apartments (big ask, I know) and maybe physical garages
6. More Leg Cyberware like Deus Ex's Icarus Dash augment, maybe simply a fast running cyberware, wall running that was cut could be reintroduced as end-game content to not impact the early level design.
7. More incentive to eat and try different food.
8. Seeing V in reflections - I believe the reason it's not possible atm is that V looks dumb in 3rd person and to save animation costs, as well as performance reasons. But I think it's a big lost opportunity, because you customize so much, and you don't see it anywhere.
9. More open-world side activities. I know how much work that would be for how little play time worth of content, but things like Darts in Watch Dogs Legion, Football etc. In Deus Ex HR you can grab and throw the PhysX powered basket balls at the basketball court. Small stuff like that would alleviate the comparisons between this and Rockstar open worlds and just make it feel more immersive.
10. MORE SEX, MORE JOYTOYS, MORE MATURE - The world is surprisingly and underwhelmingly clean for a city that's supposed to be dark and grungy. I picked my penis to never see it again, never be mentioned. I thought they'd at least impact the after-sex scene or something. Is CDPR trying to leave this to modders to avoid adult ratings?
11. Alt+Click to sell entire stack of items.

Conclusion
9/10 when everything is working as intended. There's things that I think would've really made the game a lot better and make it a perfect 10. I believe it'll eventually get there with DLCs and Expansions... Don't give up CD Projekt Red! You guys made a really amazing game.
I'm hoping this eventually reaches CD Projekt Red, or someone who worked on the game.
Man this post is a mess... but I'm going to post it anyway because I wrote a lot lol.
Cyberpunk is amazinggggg.

PRESS START<
Hey everyone since the update in GTA this newest heist has been the most profitable and easiest way to make money. So I wanted to create a guide to help others master this heist, and to help those who are struggling with it.
Note: This guide is for new players, first timers, and anyone who is struggling to complete this heist. Please use this as reference to deepen your understanding of the heist. If you have a better strat, more power to you. This however is my strat, criticism is welcome.
So to begin, you will have to buy the Kosatka (submarine), which is located on warstock for 2.2mil. It also has upgrades you can buy but the most noteworthy upgrade is definitely the Sparrow upgrade (1.8mil) this upgrade will make traveling back and forth much easier since your sub is located in the sea.
Noteworthy things about sub:

• If you hover above your sub with a sparrow you can instantly enter it.
• You can get free snacks at the cafeteria
• You can fast travel; if you never completed the heist its 10k, after completion its 2k
• Your toreador vehicle can enter through the bottom
• You can call dingy if you can not afford the sparrow

After you get the sub you’ll be introduced to characters and will have to go to LSIA, where you will travel to Cayo Perico, after you arrive everything henceforth is pretty straightforward. After you escape the party you will have to enter the main island through the checkpoint ( Google Boom Gate), PLEASE DO NOT SWIM AROUND THE ISLAND. You will waste so much time doing so, just run through the gated door next to the checkpoint and avoid entering enemy cones, watch for vehicles and watchtower cones. The biggest things to scope out are the infiltration points and exfil points; the airport strip is already marked, the biggest point to scope out after you hack the cameras is the drainage tunnel. This will require swimming, the drainage tunnel is located on the coast of El Rubio’s compound you can dive and find it, Pavel will give you a vocal cue when you find it. When you are looking through cameras after hacking make sure to cycle through every camera, turning to find secondary points, stop until you get back to the Panther Cage. Don’t bother scoping anything else like bolt cutter’s or grappling hooks, because you will not need them. I added a map of Cayo Perico to show where everything is, please note that there are many ways to do this heist this is just my way of doing so. After you found the drainage tunnel and finished your objective, get caught and make your way to the airport strip to leave. Also note there are different Primary targets the first time will always be the files the second will vary, look in the tips for scoping out to see the rankings.
​
Credit to Sportskeeda
Tips for Scoping out

• On your second time doing the heist you will start at the air strip. There are 2 dirt bikes located at the strip one by the entrance to the strip and one by the solar panels next to the power station. You can take the bikes and drive up and over the checkpoint to get to the communications tower faster. At the checkpoint to the left there's a little stone wall in front of the guards tower. You can drive the bike up the ledge and get over it, for a quicker way you can also drive the bike up the ledge a little bit in front of the wall to also get over.
• If you solo, scope out any important secondary point. There's a secondary point in the airstrip hangar, at the entrance of the hangar look right to see the box you can climb, use this to get to the second floor to get the secondary point. (To clarify check the targets spawns and only mark coke and weed; do not mark weed at the strip and north dock only coke, mark weed at the main dock)
• When you are heading to the communications tower to hack, pay attention to the guard, if there is a guard, the box is located up the tower, if there is no guard it's on ground level.
• You can kill yourself or get caught to go back to the airstrip.
• You can also poison the guards water supply to weaken them but unless you're going aggressive don’t bother.
• There are boats out in water you can steal but I would only do this to scope out the drainage tunnel the first time.
• You only need to scope infiltration points and exfils points once, secondary targets and tools must be scoped out every time.
• Secondary targets and tools are RNG based so if you're looking for tool and it’s not there it’s because of RNG
• Secondary Targets Rank: Gold>Cocaine>Paintings>Weed>Cash
• These also will fill your bag different
• Gold=66% Cocaine=50% Paintings=50% Weed=37.5% Cash=25%
• The price for secondary targets are RNG based but Gold, cocaine, and Paintings have the most value
• Secondary Targets Values are RNG based.
• Gold=332k, Cocaine=220k, Paintings=189k, Weed=147k, Cash=80k-90kCredit goes to u/FMT_WL1
• Primary Targets Ranked: Panther Statue 1.9M>Pink Diamond 1.4M> Bearer Bonds 1.1M> Ruby necklace 1M> Tequila 900k

Preps
In order to start the heist you must do preps, for this heist you can do however many you want but for this guide you will only need to do 5. Keep your sub in Los Santos until the fifth prep mission, if you decide to do the longfin prep you can keep your sub at Los Santos.
Prep 1/ The Cutting Torch:
This prep mission is pretty straightforward, head to the construction site and land close enough. Before heading in, try to locate the yellow hard hat and put it on, this will make the enemy non-hostile, which makes for an easy mission. Your job is to locate the torch in a tool box. You can find it by looking in the box, it's a blue torch, search the box and head back to your sub. Also when searching for the box try to avoid staying in the enemy cones for too long and bumping into workers because this will make the enemies hostile if you do these.
Prep 2/ Safe Code or Plasma Cutter
There are two missions. The mission will vary on your primary, if you have the bearer bonds it’s the safe code, anything else it’s the Plasma Torch.
Safe Code Mission: Head to the casino at the entrance, after entering turn left and enter the elevator (if you have a penthouse you can go up without entering the parking garage). You will have to find a car in the parking garage. It's a yellow cheap car, it never changes. After finding it you will get the card which will allow you to head up into the penthouses, after getting up there search for two guards and head shot with a suppressed weapon. If done right you will calmly walk into the apartment, you can then search the penthouse for the target, he will never change. It's a guy with a cowboy hat, kill him and leave the penthouse, you will have to fight your way out. If you slam into the entrance of the penthouse you will have to fight your way in. After getting the code get back to your sub.
Plasma Cutter Mission: This is pretty straightforward, for ease take your oppressor instead of your Sparrow for higher mobility. You will have to head to the office to get the plasma cutter, but it’s not there. Pavel will instruct you to find the board and take a picture of it, the board is easy to find. Afterwards he will locate them and ping it on your map, they usually always spawn near Vinewood hills or the beach. Take them out with your oppressor missiles and fly over the bag and leave cause they will spawn two cars to shoot you.
Prep 3/ Fingerprint Cloner: This mission is simple, you will have to head to a location on your map, outside are two cameras, ignore them and walk into the garage, after entering take cover behind the box forward and blind shot everyone with your shotgun. After the enemies are dead hack the laptop in the back and head to the archives. Outside the archives are cameras, shoot them and go inside. Pavel will tell you that you're looking for a small card, it always spawns in the back in the desk square, grab it and head back.
Prep 4/ Weapon Load out: Always buy the suppressors, as for which load out I suggest the Conspirator due to the sticky bombs (there is a bug where you will get suppressors without buying them, just in case purchase it to be safe). There are two possible missions you can be given. One is in Los Santos in an office, for the other you will have to follow a Valkyrie up North.
Weapons Possible Mission 1: Pavel will send you to an office in Los Santos you can either go through the ground entrance or the roof, I suggest the roof entrance but no matter what you will have to fight inside. Once inside clear the office and head to the back to find the gun safe, it’s always located left of the desk on the wall, hack the laptop on the desk and open the safe. Grab the weapons and leave. If you enter on the roof you can fly back but two chopper’s will spawn, shoot their gunman on the sides and hellies will be useless. Another suggestion is to leave immediately, and snack up to restore health. On ground level the hellies will still spawn again shoot the gunman and head back to the sub.
Weapons Possible Mission 2: You will have to head to Elysian Island to find the Valkyrie you do not need to stay close to it. You can predict it’s direction and head North to clear the camp on foot, also avoid destroying the Avenger and the Valkyrie. Do not destroy the Valkyrie until it becomes a target on your mini map or you will fail the prep. After clearing the camp head into the Avenger and kill the enemies, afterwards parachute out and leave before more Merrywheather show up.
Prep 5/ Kosatka: ( You can also do the Longfin, but I prefer Kosatka as an approach vehicle.)
This is a simple mission, after starting it head into your sub driver seat and fast travel to the nearest location near the ping. After you arrive dive your sub over to the location, once you get near get on your periscope and missile the boats and the helli. You can sink your sub and engage auto-pilot under water giving you better access to the enemies sub. Try to avoid beaching your sub on shallow water and put it in the middle of the yellow circle. Leave the driver seat and exit your sub, dive into the water and look for the other sub with a yellow marker on top. After entering the enemies sub you must locate the jammer. You have two paths, one on the right, this is usually where it spawns, take the ladder down and watch your corners cause enemies are brutal in this mission. After entering the engine room look for a black box with a blue screen at the bottom of the stairs if it's not there head back the way you came. Take the left path and make your way to the control room WATCH THOSE CORNERS. If it's not there head to the back of the control room and take the stairs down, follow the path it will lead you into the torpedo room, that another spawn. Leave and head back to your sub.
Prep 5/ Longfin
This mission is located in Los Santos basically you can take a phantom (Semi-truck) to the police station to pick up a boat of which you can use as an approach for the heist. This mission is simple: you basically go and pick up a phantom, afterwards you drive to impound to pick up the longfin. You will be met with enemies. The one I did was the cop impound, you can enter with your phantom and drive out. It's best to clear the area, and let the cops kill you for an easier delivery (you can't call Lester). You can use your own Phantom wedge to clear vehicles out of the way.
(during the heist you can use this get loot before you enter the drainage tunnel , this can be quicker way if your loot is out the way)
This includes the scope out and the preps
This includes the scope out and the preps
Tips For Preps

• The biggest tip is the Sparrow, this will make prepping a joke, the only time you won’t need it is during the plasma cutter and Kosatka missions, but that's due to mobility.
• You can see the cutting torch it’s blue
• You can blow up the Valkyrie and end the mission to get the office mission to save time, I highly suggest this ( I do this mostly because you have to follow the helli up North and wait for it to land.)
• The preps are the same, they never change
• Save the Kosatka heist for last so you can do all 4 preps in Los Santos

The Heist
Time to Start the Heist. Go to screen and tab to Finale and shift over to continue to start the mission. Once you get to the selection process pick your options. It should be Kosatka or Longfin, Drainage, Drainage, Main docks or Kotsatka, and Day Time (there's very little difference between day or night). If you're playing with others you must hurry through the selection screen because if you take too long the cuts will reset due to a bug.
Squad Run
When you begin the mission you will have to make your way to the drainage tunnel, if you chose the Kosatka you will have to swim to the tunnel, but if you chose the Longfin you will have to drive the boat to the tunnel. Once you arrive you will have to cut the bars at the gate, a suggestion to do this is to go in a circle three times and cut whatever remains. Afterwards swim through the tunnel and enter the compound.
Compound
Once you enter the compound you will have two directions to go, the left or the right. My way is to go to the left, up the stairs is a guard next to the storage staring out at the water, head shot him and make your way to the courtyard. If you followed my instructions the two guards at the pool will be to your left. In the courtyard there should be a guard coming, wait for him to stop and head shot him. After that, ready your shot at the two guards at the pool, choose your target. Since you're in a squad, ready your shot, as a suggestion one person can count down from three to one to shoot at the same time to eliminate any mistakes ( these two guards usually drop the gate keys). The next is to eliminate the juggernaut, the way to identify him is by his red cone and red skull icon. He can be killed by a single headshot, if you and your squad were quick with the guards at the pool he should be arriving, take him out. In front of the pool there are two separate guards, one will be in front of the office building to identify him, the camera is facing the pool, if you time it correctly he will be to the right of the camera making for an easy elimination. The other guard is North East of the front of the pool, or to the right of the guard you just killed. You can eliminate him if you want too, the reason I do so is because me and my mates can all access the storages without worry. Next are three guards at the office, to identify them they will have red cones. One of the guards will be moving North towards the main gate and then will move South towards the pool. You have two options, one is to wait for him to head North and take him out, or you can head shot him when he’s coming South. To achieve this there are stairs directly in front of the pool, if you take the stairs up to the right you now have enough elevation to see the guards head ( this is tricky to explain which is why I will also have a video example for visual clarification.) After taking the guard out you can head up the stairs into the office area, once up the stairs head to the right, for clarification the pool will be to the left and main gate to your right. Head down the corridor if you have done this correctly the guards back will be facing you, take him out. To your left are stairs that leads to the office, take them up, at this point the guard at the top will start to move. You have two options, one you can wait behind a corner and hit the guard or if you are quick enough the guard will stop for a brief moment, giving a chance for an easy headshot. At this point you can enter the office, where you can grab the second keycard, the first keycard is dropped by any guard you have killed ( it usually drops on the first kill, but this is RNG based). In the office there are three things you can do, one is you can hack the elevator which leads to the basement, ignore this hack. The other things are either a painting that can randomly spawn in the office, and a safe on the right wall in the back of the office. Open the safe to get anywhere between 50k to 100k, THIS DOES NOT TAKE SPACE. When you have everything, start to loot up and fill your bag by going to the storages located around the compound, to open the storages you will need the two keycards and two people. You and your squad mates will have to swipe your card at the same time to open the door, another suggestion is to use the three to one countdown to sync swipes. The South Storage will have a guard moving, the guard is located to the left of the two guards you killed at the pool, take him out and watch for the camera. After you are done, please make sure to save space for the basement storage, make your way to the basement gates, they are located beneath the office building to the left and right, it does not matter which gate you choose. Once you are in the basement you will be presented with a hack, it may look daunting but in fact it is rather simple, I suggest matching the top first and making your way down. Afterwards loot up and grab the Primary Target, it is really straightforward to do so. At this time Pavel will tell the players that more guards have arrived, if you have followed thus far, you do not have to worry. Exit the basement, and head North to the main gate there should two guards, one will be moving the other stationary. You can take the stationary guard, you can also take the guard moving but if you and your squad can make it to the gate without doing so, go ahead. The host will be prompted to select the escape route, select it and a cutscene will begin. After you will be located outside the compound.
Kill in this order
Outside The Compound
You and your squad will be outside, if you are satisfied with your loot head left to the coast, you can jump off the cliff into the water. Once in the water you can swim off the island ,just keep heading straight and eventually you will have escaped. You can also try to steal a boat; note that some have claimed that boats may not spawn but if you manage to grab a boat this can make getting to and from much quicker. If you are missing loot head forward and take the guard next to the bike out, one person will have to head left toward a guard near a helli take him out and plant four stickies on the chopper. At the same time the other members will turn right towards the checkpoint, there should be three guards two together and one separate, and a camera behind the two guards. Take the one separate out, then the two guards, and the camera. Around the checkpoint are three bikes plus the bike with the very first guard killed. One of the bikes is hidden to the left of the checkpoint booth the other is directly in front. Start making your way towards the main docks, turn right into the jungle the moment you leave the stopping checkpoint. Pay attention to the guard tower to your right and avoid his cone, at this time Pavel will tell the squad that El Rubio’s helli is on the move, activate the stickies and he will retreat away from the island. Once you are close enough to the docks go on foot, your objective is to loot and take the boat off the island. There are two secondary loot locations, one is a warehouse with a guard and camera outside, take them out and loot. The other is located to the right with two separate guards, please refer to Sportskeeda map to see the location. Take them out and loot. Afterwards there are 3-4 guards you have to take out at the docks, to leave without alerting the guard. Two guards standing next to the boat, and one or two stationary guards looking out at the water. After clearing the guards, grab the boat and escape Cayo Perico. Congrats you have now completed the heist.
Note: You can approach the compound in any way you choose, my way is a bit complicated but with practice you can clear the compound at the same time as other routes. Feel free to adjust the route in anyway, my route is just a reference to get an idea as to how to approach the compound.
Note: I do it the same exact way when I solo, but since I’m solo I can skip guards and head to my objective. For the Solo run I go for cocaine, you NOT have to do this. I do this to maximize my profit, and since I am competent in my abilities I can clear the mission without many mistakes.
Solo Run
The strat is the same except it will be harder to take out the two guards by the pool, the major difference is you can not open the storage's to get gold or loot, you might be lucky to get painting in the office but that's RNG. A good tip when taking on double guards is to find a good angle, after killing one the other will flinch, he will prop his head up giving you the shot. You can scope the rest of island to find the most profitable loot which is cocaine, if there is none then get weed and cash (by scoping out I’m referring to checking the spawns for coke, if there is none at North docks and the Air Strip I ignore them, I do not mark every item only Coke and any profitable items at Main Docks). After leaving the compound there will be a guard in front of you next to a bike, kill him. Turn left and head to the next guy next to a helli, kill him and plant four stickies on the heli, do not activate them yet. Go back the way you came, there will be three guards at a checkpoint two together, one standing away. Kill the one standing away and then prepare to kill the two guards, after their dead shoot the camera and jump over the stop rail. You will have to be quick because a car will drive towards the checkpoint so make sure to do all that quickly. You have two options: you can swim off the island and finish the heist, or you can head to Main Docks to fill your bag. If you chose the latter run North East into the jungle towards the guards tower, but far enough away so he can’t see you. On your way to Main Dock Pave El Rubio helli will show up on the map, wait for Pavels vocal cue when he tells you that Rubio is in his helli, and then activate your stickies, boom Rubio will retreat. Now you can make it to your objective in peace. You can loot at the Marijuana fields but you may have to take out three guard towers and a single camera, as well as two guards near the fields. I’ll leave this to your gut if you think you can make it to the warehouse without messing up please do so. If you want to head to North Dock and the Airstrip you either can swim there which will eat a lot of time or you can take the boat at the docks to get there faster. Trade off is that if you swim it will take up time, but if you take the boat you will have to clear out guards to safely remove the boat from the dock. If you are satisfied with anything you get then just clear the area with loot and swim or steal the boat. This is for the Airstrip if you do not plan on going here IGNORE this. The Airstrip is an easy place to navigate since a lot of the guards are far from each other so you can clear the airstrip easily. There are two loot spawns one at the hangar with one guard, and a warehouse with two separate guards. There's guard outside the hangar kill him, and go inside, if your loot is on the second floor, look for a forklift and pick up a box lift and it up then press the box against the back of the hangar below a blue tarp you can then climb the lift and the box to get access to the loot. The other airstrip loot spawn is an easy place to clear, one guard will be moving you can head shot him from the hangar, at the warehouse there’s a camera shoot it and inside the warehouse is a guard questioning his career choice, kill him. If you need to head to North Dock head there by bike or by foot, you can loot without killing any guard. After you're done just swim off the Island, or take the boat. Congrats, you have just completed the heist solo.
Note: I will be adding a second strat to clear the compound, the reason for this is because a Redditor provided the strat. I do not mind adding his strat, but I must remind everyone that you can tackle the heist in any way you feel comfortable with.
I missed that gate keys, so I killed more than I should have.
Solo Run Second Strat:
Essentially, it is the same as the other one, except for going left you go right. Your first target are the two guards at the pool. They should be to the right of you, find a good angle and head shot the first one, wait for the second guard to finish flinching and kill him. The juggernaut should be making his way towards you, wait for him to exit the camera’s view and kill him. If the gate key drops pick it up and kill the guard in front of the pool he should be past the camera. Take out the camera and wait for the moving red cone guard to turn his direction North, once he turns around go up the stairs and kill him. Move towards the second red cone guard his back should be facing you, hit him and ascend the stairs. The last guard on top should be moving. You can either wait behind the corner and hit him or speed around the corner to head shot him, it’s up to you. Loot the office safe and make your way to the basement. Finally, use the gate keys to open the basement, hack and grab the primary target. Afterwards head up towards the main gate, a new guard will spawn, you can wait for the moving guard to move out of range, and kill the stationary guard. From there you can run to the gate and exit the compound.
I had brain fart at the hacking lmao
Heist Tips

• You can swim off the island from any direction
• You can steal boats for faster escape but that's up you
• You can sticky El Rubio’s helli for to get him to retreat
• In the compound you can jump ledges after clearing the enemies
• For double guards, get a good angle after you head shot one guy the other will flinch, you can get the shot slightly after, or you can risk shooting him until he’s dead.
• Guards do not react to dead bodies, in day time their visibility is the same as night, an Isolated guard can’t alert if everyone is dead. You can run, guards will only react if you're close, if you miss a shot and it gets near a guard or makes noise this will alert.
• You can jump into the ocean to die quickly if you alert inside the compound
• If you find a key you can open the desk to get a golden gun
• If your underwater and a patrol boats cone is on you, they can’t see you
• Cones can be obstructed by objects
• ? Civilians may be able to alert guard?
• Solo is more profitable than playing with friends due to not sharing a cut
• If you don’t have to kill don’t, less interaction is good
• Being stealthy is the best way, if you alert restart
• You can aim in and hold the sprint button to walk faster
• To activate hard mode, you have to start the heist when it becomes available
• Try to avoid killing guards near the camera cones, the reason being is because this can alert the guards if the camera sees the dead body. Ironically, guards do not alert they seem one.

Game Over>
That's it ladies and gentleman, I hope this guide has helped anyone. I’m aware I’ve definitely went too in depth in this guide but I enjoy making it, Happy Grinding -Leaus